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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF7
All Species:
16.06
Human Site:
Y428
Identified Species:
39.26
UniProt:
Q92985
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92985
NP_001563.2
503
54278
Y428
Q
R
R
G
S
P
R
Y
T
I
Y
L
G
F
G
Chimpanzee
Pan troglodytes
XP_001147267
439
48559
Y364
Q
R
R
G
S
P
R
Y
T
I
Y
L
G
F
G
Rhesus Macaque
Macaca mulatta
XP_001092569
500
56291
F395
Q
T
N
A
P
P
P
F
E
I
F
F
C
F
G
Dog
Lupus familis
XP_540526
284
31613
L219
Y
L
G
F
G
Q
D
L
S
A
G
R
P
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P70434
457
51203
Y382
R
R
Q
G
S
P
H
Y
T
I
Y
L
G
F
G
Rat
Rattus norvegicus
NP_001028863
455
50697
Y380
R
R
Q
G
S
P
H
Y
T
I
Y
L
G
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508806
462
52633
M396
V
I
P
V
V
A
R
M
I
Y
E
M
F
S
G
Chicken
Gallus gallus
Q90643
491
54423
F419
R
R
E
R
S
P
D
F
T
I
F
L
C
F
G
Frog
Xenopus laevis
NP_001079588
466
52659
Y388
T
R
K
S
S
P
Q
Y
H
I
W
M
C
L
G
Zebra Danio
Brachydanio rerio
NP_956971
423
49042
G358
Y
T
I
Y
L
C
F
G
E
K
L
H
D
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.7
28.2
43.7
N.A.
62.6
63.8
N.A.
28
41.5
25.8
31.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.5
41.9
48.5
N.A.
69.5
70.9
N.A.
43.1
53.2
43.3
46.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
33.3
0
N.A.
80
80
N.A.
13.3
53.3
40
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
6.6
N.A.
93.3
93.3
N.A.
20
73.3
66.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
30
0
0
% C
% Asp:
0
0
0
0
0
0
20
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
20
0
10
0
0
0
10
% E
% Phe:
0
0
0
10
0
0
10
20
0
0
20
10
10
60
0
% F
% Gly:
0
0
10
40
10
0
0
10
0
0
10
0
40
10
80
% G
% His:
0
0
0
0
0
0
20
0
10
0
0
10
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
10
70
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
10
0
0
0
10
10
% K
% Leu:
0
10
0
0
10
0
0
10
0
0
10
50
0
10
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
20
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
10
70
10
0
0
0
0
0
10
0
0
% P
% Gln:
30
0
20
0
0
10
10
0
0
0
0
0
0
0
0
% Q
% Arg:
30
60
20
10
0
0
30
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
10
60
0
0
0
10
0
0
0
0
10
0
% S
% Thr:
10
20
0
0
0
0
0
0
50
0
0
0
0
0
0
% T
% Val:
10
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
20
0
0
10
0
0
0
50
0
10
40
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _